Tuesday, March 15, 2011

Haematology

Haematology is the long-awaited, revised and updated version of the original edition first published in 1999 as part of the highly respected 'Biomedical Sciences Explained' series. This time we have a new editor as Chris Pallister has been joined by Malcolm Watson, and the book has grown by over 130 pages. Initial impression is of a very nicely presented text with a clear, uniform style throughout and numerous boxes containing mainly historical and some explanatory annotations, which add a nice touch. All illustrations are greyscale but they work well.
All of the major headings that one would expect in a book of this kind are represented, with 20 chapters in total, starting with an initial introduction to blood and haemopoiesis, followed by substantial chapters covering red cells, a chapter covering non-malignant leucocyte disorders, seven chapters covering all major areas of haematological malignancy, and finally three chapters devoted to coagulation. Each chapter begins with clearly stated learning objectives.
Chapter 3 introduces us to the concepts of anaemia and the description of red cells. On page 43 we are told that the term 'hyperchromic' is not used, but in practice it sometimes is - spherocytes do lose their area of central pallor because they are no longer biconcave, but they are often smaller than normal red cells and have an increased haemoglobin concentration, and they do look darker upon microscopic examination. Even the suggested further reading (Bain) supports careful use of this term.
Chapter 4 provides sound coverage of the disorders of iron metabolism and the relationship between hepcidin and ferroportin that would not have been found in any book published in 1999.

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